Selected Publications
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Sepsis subclasses: A framework for development and interpretation
DeMerle, K. et al. Critical Care Medicine. Feb 2021.
Validation of inflammopathic, adaptive, and coagulopathic sepsis endotypes in Coronavirus disease 2019
Sweeney, T. et al. Critical Care Medicine. Feb 2021.
A novel method for classification of tabular data using convolutional neural networks
Buturovic, L. and Miljkovic, D. BioRxiv. Jan 2021.
Evaluation of Bayesian optimization to select predictive models of acute infection and in-hospital mortality
Mayhew, M. et al. Pac Symp Biocomput. Jan 2021.
Outcomes of metabolic resuscitation early treatment of sepsis (ORANGES) trial
Iglesias, J. et al. J Personalized Medicine. Dec 2020.
Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections
Thair, S. et al. Science Direct. Dec 2020.
A multi-mRNA host-response molecular blood test for the diagnosis and prognosis of acute infections and sepsis
Ducharme, J. et al. Journal of Personalized Medicine. Dec 2020.
A 29-mRNA host response test from blood accurately distinguishes bacterial and viral infections among emergency department patients
Safarika, A. et al. medRxiv. Dec 2020
A 6-mRNA host response whole-blood classifier trained using patients with non-COVID-19 viral infections accurately predicts severity of COVID-19
Buturovic, L. et. al. medRxiv, Dec. 2020.
Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections
Thair SA, He YD, Hasin-Brumshtein Y, et al. medRxiv 2020.06.18.20131326.
Selected Abstracts
A baseline gene expression-based prognostic for anti-TNFα therapy response in patients with inflammatory bowel disease
Sakaram S, et al. IBD supplement
January, 2021
Development of a 29-mRNA loop mediated isothermal amplification assay for the rapid diagnosis of acute infection and sepsis
Remmel M, et al. AMP 2020
November 16-20, 2020
Similarities and differences in the transcriptomic host response between SARS-CoV-2 and other viral infections
Thair S, et al. ID Week 2020
October 21-25, 2020
A 5-mRNA host response whole-blood classifier trained using patients with non-COVID-19 viral infections accurately predicts severity of COVID-19
Buturovic L, et al. ID Week 2020
October 21-25, 2020
A 29-mRNA host response signature accurately distinguishes bacterial and viral infections among Emergency Department patients
Safarika A, et al. e-ISICEM 2020.
September 15-19, 2020
Prospective validation of a 29-mRNA host response signature to diagnose suspected acute infections in ED patients
Galtung N, et al. EUSEM Virtual 2020.
September 19-22, 2020
A mRNA host response signature accurately distinguishes bacterial and viral infections among Emergency Department patients.
Safarika A, et al. ASM Microbe 2020, Greece BVN-2.
June 22 – August 17, 2020
An ultra-rapid host response assay to discriminate between bacterial and viral infections using quantitative isothermal gene expression analysis
Rawling D, et al. 2019 ECCMID.
April 13-16, 2019
Diagnosis of acute bacterial and viral infections using a 29-mRNA neural network
Mayhew M, et al. 2019 ECCMID.
April 13-16, 2019
Multiplex RT-qPCR for diagnosis and risk stratification of acute infection and sepsis using a 30-mRNA host response signature
Rawling D, et al. 2019 ECCMID.
April 13-16, 2019
Rapid host mRNA-based discrimination between bacterial and viral infection
Rawling D, et al. SAEM Western Regional Meeting
March 21‐22, 2019
Multiplexing of an 18-host-gene signature using rapid PCR for better antibiotics decision
Nie W, et al. SAEM Western Regional Meeting
March 21‐22, 2019
An ultra-rapid host response assay to discriminate between bacterial and viral infections using quantitative isothermal gene expression analysis
Rawling D, et al. 2018 IDWeek
October 3-7, 2018
Rapid multiplex host gene expression profiling to discriminate bacterial from viral infections.
Nie W, et al. 2018 IDWeek
October 3-7, 2018
Cost effectiveness of emergency department use of a novel multi-mRNA assay for diagnosis and risk assessment of acute respiratory tract infections and Sepsis
Stojanovic I, et al. Intnl. Sepsis Forum 2018
October 1-3, 2018
Dual-cohort independent validation of a novel 12-mRNA score for sepsis prognosis
Sweeney T, et al. International Sepsis Forum 2018
October 1-3, 2018
Survey-based assessment of emergency room physician practices for patients with suspected infection and sepsis
Schultz, et al. EUSEM 2018
September 8-12, 2018
A host gene signature for diagnosis and risk stratification of acute infection and sepsis at hospital admission: HostDx™ Sepsis
Liesenfeld O, et al. EUSEM 2018
September 8-12, 2018
Integration of next-gen sequencing, viral sequencing, and host-response profiling for the diagnosis of acute infections
Cheng H, et al. ID Week 2017
October 7, 2017
The derivation and validation of three novel sepsis molecular subtypes to help guide precision therapies
Sweeney T, et al. Sepsis 2017
September 11-13, 2017
Host-response biomarkers for diagnosing acute infections
Sweeney T, Khatri P, MHSRS
August 28-29, 2017
Prospective validation of the sepsis metascore for diagnosis of infections post traumatic injury
Sweeney T, et al. American Surgical Congress
February 7-9, 2017